Midtown for first-timers, close to the sights and subway lines; Lower Manhattan for the harbor and calmer evenings; Chelsea and the West Village for food and the High Line; the Upper West Side for Central Park and a quieter pace.
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Central for every day of this plan and full of subway lines, but crowded and noisy around Times Square.
Hotels in MidtownClose to the harbor ferries and the 9/11 Memorial and quiet at night, though far from Central Park.
Hotels in Lower ManhattanWalkable streets, good food and the High Line, with fewer big hotels and higher prices.
Hotels in Chelsea and the West VillageLeafy and right beside Central Park, but a longer ride to Lower Manhattan and Brooklyn.
Hotels in Upper West SideStay in Midtown near a subway hub such as Grand Central or Times Square: every day of this plan starts or ends a short ride away.
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