Mitte for first-timers near the main sights; Friedrichshain and Kreuzberg for nightlife and food; Charlottenburg for a calmer West Berlin base.
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Walkable to the Brandenburg Gate, Museum Island and Hackescher Markt, but busy with visitors from morning to night.
Hotels in MitteMarket halls, bars and the East Side Gallery on the doorstep, though nights around Simon-Dach-Strasse can be loud.
Hotels in Friedrichshain and KreuzbergKurfürstendamm, Savignyplatz and the palace in the west, a longer ride from the eastern sights.
Hotels in CharlottenburgStay in Mitte, between the Brandenburg Gate and Hackescher Markt, so the first two days start within a short walk or tram ride.
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