Ciudad Vieja for the old-town sights on foot; Barrio Sur and Parque Rodó between the old town and the beaches; Pocitos for the beach and the Rambla.
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Closest to Plaza Independencia, the Teatro Solís, MAPI and the port market, but farther from the beaches.
Hotels in Ciudad ViejaBetween the old town and the coast, near the national art museum, and a taxi ride from the northern sights.
Hotels in Barrio Sur and Parque RodóOn the beach and the Rambla, but a taxi ride of about 20 min from Ciudad Vieja.
Hotels in PocitosStay in or near Ciudad Vieja and Plaza Independencia, so day 1 starts on foot and taxis cover the longer hops on day 2.
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